| Date | Age | Event | Bishop | Title | Current Title |
| unknown | | Born | Scipione Agnelli † | | Bishop of Casale Monferrato, Italy |
| 23.0 | Professed | Antonio (Marcello) Barberini (Sr.), O.F.M. Cap. † | Member of Order of Friars Minor Capuchin | Cardinal, Major Penitentiary of the Apostolic Penitentiary |
| Born | Prospero Caffarelli † | Rome | Cardinal, Cardinal-Priest of S. Callisto |
| Born | Bernardo Cardona † | | Bishop of Gerona, Spain |
| Born | Pietro Carpegna † | Scaolini | Bishop of Gubbio, Italy |
| Born | Maurizio Centini, O.F.M. Conv. † | Asculan | Bishop of Mileto, Italy |
| Born | Alessandro Cesarini (Jr.) † | Rome | Cardinal, Bishop Emeritus of Viterbo e Tuscania, Italy |
| 19.0 | Ordained Priest | Pietro Emo, C.R. † | Priest | Bishop of Crema, Italy |
| Born | Christophorus de France † | Mechlinien | Bishop of Saint-Omer, France |
| Born | Marcantonio Franciotti † | Lucca | Cardinal, Bishop Emeritus of Lucca, Italy |
| 24.2 | Ordained Priest | Jakob Fugger † | Priest of Augsburg, Germany | Bishop of Konstanz {Constance}, Germany |
| Resigned | Angelo Gradi, O.F.M. Conv. † | Bishop of Nona (Nin), Croatia | Bishop Emeritus |
| Born | Giovanni Battista Indelli † | Monopoli | Bishop of San Marco (Argentano), Italy |
| Appointed | Guillaume Le Blanc † | Bishop of Grasse, France |
| Died | Anton Manicir † | Auxiliary Bishop of Gurk, Austria |
| Resigned | Mateus de Medina, O. Carm. † | Archbishop of Goa, India | Archbishop Emeritus |
| Born | Antonio Nusco (Nuseo) † | Sassari | Bishop of Alghero, Italy |
| Born | Alessandro Orsini † | Castle of Bracciano | Cardinal, Cardinal-Deacon of S. Maria in Cosmedin |
| Born | Papirio Silvestri † | Cingulan | Bishop of Macerata-Tolentino, Italy |
| 52.3 | Appointed | Cesare Speciano (Speciani) † | Apostolic Nuncio to Germany | Bishop of Cremona, Italy |
| Born | Eugene Sweeney † | | Bishop of Kilmore, Ireland |
| Resigned | Martinho de Ulhoa, O. Cist. † | Bishop of São Tomé e Príncipe | Bishop Emeritus |
| Died | Francisco de Vitoria, O.P. † | Bishop of Córdoba (Tucumán), Argentina |
| Jan | | Born | Giulio del Pozzo † | | Bishop of Accia and Mariana, France |
| 1 Jan | | Died | Juan Manual Martínez de Manzanillo, O.P. † | Bishop of Coro, Venezuela |
| 6 Jan | 44.0 | Died | Juan Hurtado de Mendoza † | Cardinal, Cardinal-Priest of S. Maria in Traspontina |
| 21 Jan | | Born | Francesco Boncompagni † | Sora | Cardinal, Archbishop of Napoli {Naples}, Italy |
| 29 Jan | | Died | Horatius Sanminiato † | Archbishop of Chieti, Italy |
| 30 Jan | 55.9 | Elected | Ippolito Aldobrandini (Sr.) † | Pope (Roma {Rome}, Italy) |
| 2 Feb | 55.9 | Ordained Bishop | Ippolito Aldobrandini (Sr.) † | Pope (Roma {Rome}, Italy) |
| 6 Feb | 31.8 | Appointed | Guido Pepoli † | Cardinal-Deacon of S. Eustachio | Cardinal, Cardinal-Priest of S. Pietro in Montorio |
| 7 Feb | 64.1 | Died | Girolamo della Rovere † | Cardinal, Archbishop of Torino {Turin}, Italy |
| 9 Feb | 56.0 | Installed | Ippolito Aldobrandini (Sr.) † | Pope (Roma {Rome}, Italy) |
| Appointed | Rutilio Benzoni † | Bishop of Recanati-Loreto, Italy |
| Resigned | Galeazzo Moroni † | Bishop of Recanati, Italy | Bishop of Macerata-Tolentino, Italy |
| 58.1 | Ordained Bishop | Juan Bautista Pérez Rubert † | Bishop of Segorbe, Spain |
| 14 Feb | 42.6 | Appointed | Francesco Maria Bourbon Del Monte Santa Maria † | Cardinal-Priest of S. Maria in Ara Coeli | Cardinal, Cardinal-Bishop of Ostia (-Velletri) |
| 51.1 | Appointed | Giovanni Battista Castrucci † | Cardinal-Priest of Ss. Giovanni e Paolo | Cardinal, Archbishop Emeritus of Chieti, Italy |
| 56.7 | Appointed | Alessandro Ottaviano de’ Medici † | Cardinal-Priest of S. Prassede | Pope (Roma {Rome}, Italy) |
| 16 Feb | | Ordained Bishop | Claudio de Curtis † | Bishop of Crotone (Cotrone), Italy |
| 45.0 | Appointed | Girolamo Mattei † | Cardinal-Priest | Cardinal, Cardinal-Priest of S. Pancrazio |
| 53.1 | Ordained Bishop | Lorenzo Asensio Otaduy Avendaño † | Bishop of Lugo, Spain | Bishop of Avila, Spain |
| 17 Feb | | Appointed | Antonio Maria Graziani † | Bishop of Amelia, Italy |
| 50.1 | Appointed | Pedro Martins, S.J. † | Bishop of Funay (Funai), Japan |
| Appointed | Francisco de Villanova, O.F.M. † | Bishop of São Tomé e Príncipe |
| Died | François de Wallon-Capelle † | Bishop of Namur {Namen}, Belgium |
| 21 Feb | | Died | Girolamo Mannelli † | Bishop of Nocera Umbra, Italy |
| 26 Feb | | Died | Giovanni Goffredo Ginod † | Bishop of Aosta, Italy |
| 27 Feb | 56.2 | Appointed | Jean-François Bordini, C.O. † | Bishop of Cavaillon, France | Archbishop of Avignon, France |
| Died | Marcantonio Venier † | Archbishop of Zadar (Zara), Croatia |
| 29 Feb | | Died | Giovanni Battista Santorio † | Bishop of Tricarico, Italy |
| 4 Mar | | Appointed | Ferdinando D’Avila, O.F.M. † | Bishop of Rethymo, Greece | Bishop of Ascoli Satriano, Italy |
| 17.0 | Installed | Giovanni Antonio Facchinetti (Jr.) † | Cardinal, Cardinal-Priest of Ss. Quattro Coronati |
| Appointed | Roberto Pierbenedetti † | Bishop of Nocera Umbra, Italy |
| Appointed | Matteo Sanminiato † | Archbishop of Chieti, Italy |
| Appointed | Giovanni Vitelli, C.R. † | Coadjutor Bishop of Carinola (Calina), Italy | Bishop of Capaccio, Italy |
| Appointed | Giovanni Vitelli, C.R. † | Titular Bishop of Tiberias | Bishop of Capaccio, Italy |
| 5 Mar | 55.2 | Died | Gerolamo Ragazzoni † | Bishop of Bergamo, Italy |
| 46.3 | Died | Hermann von Schaumberg † | Former Bishop-Elect of Minden, Germany |
| 9 Mar | | Appointed | Ottavio Mirto Frangipani † | Bishop of Tricarico, Italy | Archbishop of Taranto, Italy |
| 45.1 | Appointed | Girolamo Mattei † | Cardinal, Cardinal-Priest of S. Pancrazio |
| 39.7 | Appointed | Ottaviano Paravicini † | Cardinal-Priest of S. Alessio | Cardinal, Bishop Emeritus of Alessandria (della Paglia), Italy |
| 39.7 | Appointed | Flaminio Piatti † | Cardinal-Deacon of Ss. Cosma e Damiano | Cardinal, Cardinal-Priest of S. Maria della Pace |
| 17 Mar | | Appointed | Alfonso Guerra, O.M. † | Bishop of Michoacán, México |
| 19 Mar | | Born | José Argáiz Pérez † | Arnedo | Archbishop of Granada, Spain |
| 24 Mar | | Died | Mariano de Racciaccaris, O.F.M. † | Bishop of L’Aquila, Italy |
| 3 Apr | | Appointed | Alvise Baroccia † | Archbishop of Zadar (Zara), Croatia |
| 8 Apr | | Appointed | Orazio Bellotti, O.F.M. Conv. † | Bishop of Nona (Nin), Croatia |
| Appointed | Giambattista Milani, C.R. † | Bishop of Bergamo, Italy | Bishop Emeritus |
| 10 Apr | | Ordained Bishop | Gilbert Genebrard, O.S.B. † | Archbishop of Aix, France |
| 15 Apr | 65.3 | Appointed | Pedro de Aragón † | Bishop of Lérida, Spain |
| Born | Francesco Maria Brancaccio † | Canneto | Cardinal, Bishop of Porto e Santa Rufina, Italy |
| 58.3 | Appointed | Camillo Daddeo (Doddeo) † | Bishop of Fossano, Italy |
| 22 Apr | | Appointed | Orazio Giraldi † | Bishop of Comacchio, Italy |
| 26.3 | Appointed | Filippo Spinelli † | Coadjutor Bishop of Policastro, Italy | Cardinal, Bishop of Aversa, Italy |
| 26.3 | Appointed | Filippo Spinelli † | Titular Bishop of Colossae {Rhodes} | Cardinal, Bishop of Aversa, Italy |
| 24 Apr | | Born | Marcos Ramírez de Prado y Ovando, O.F.M. † | Madrid, Spain | Archbishop of México, Federal District |
| 29 Apr | | Born | Deodato Scaglia, O.P. † | Brixiae | Bishop of Alessandria (della Paglia), Italy |
| 2 May | | Died | Alvise Baroccia † | Archbishop of Zadar (Zara), Croatia |
| 6 May | 26.3 | Ordained Bishop | Filippo Spinelli † | Titular Bishop of Colossae {Rhodes} | Cardinal, Bishop of Aversa, Italy |
| 7 May | | Died | Marcantonio Gonzaga † | Bishop of Casale Monferrato, Italy |
| 23.5 | Ordained Priest | Richard Smith † | Priest | Vicar Apostolic Emeritus of England, Great Britain |
| 10 May | 31.4 | Ordained Priest | Johann Konrad von Gemmingen † | Priest of Augsburg, Germany | Bishop of Eichstätt, Germany |
| 11 May | | Appointed | Stefano Bagliani (Baliano) † | Bishop of Brugnato, Italy |
| 36.4 | Appointed | Maffeo Gambara † | Bishop of Tortona, Italy |
| 21 May | 52.4 | Appointed | Andrés de Ubilla, O.P. † | Bishop of Chiapas (Ciudad Real de Chiapas), México | Bishop of Michoacán, México |
| 22 May | 67.4 | Appointed | Jerónimo de Escobar, O.S.A. † | Bishop of León en Nicaragua |
| Appointed | Alonso Fernández de Bonilla † | Archbishop of México, Federal District |
| Appointed | Jerónimo de Menezes † | Bishop of Porto, Portugal |
| Appointed | Francisco Santos García de Ontiveros y Martínez † | Bishop of Guadalajara, Jalisco, México |
| 25 May | | Born | Bernardo Caballero Paredes † | Medina del Campo | Bishop of Oviedo, Spain |
| 36.0 | Installed | Jerzy Radziwiłł † | Bishop of Kraków, Poland | Cardinal, Bishop of Vilnius, Lithuania |
| Jun | | Died | Jacques du Plessis de Richelieu † | Bishop of Luçon, France |
| 5 Jun | 50.4 | Appointed | Diego Monreal † | Bishop of Jaca, Spain | Bishop of Huesca, Spain |
| Appointed | Usimbardo Usimbardi † | Bishop of Colle di Val d’Elsa, Italy |
| 9 Jun | 24.9 | Selected | Charles de Lorraine-Vaudémont (III) † | Cardinal, Bishop of Strasbourg, France |
| 12 Jun | | Appointed | Settimio Borsari † | Bishop of Casale Monferrato, Italy |
| 59.4 | Appointed | Juan Fernández de Rosillo (Rovillo) † | Bishop of Verapaz, Guatemala | Bishop of Michoacán, México |
| 19 Jun | | Appointed | Horatius Acquaviva d’Aragona, O. Cist. † | Bishop of Caiazzo, Italy |
| Appointed | Sextilius Mazuca (Massuca) † | Bishop of Alessano, Italy | Bishop Emeritus |
| Appointed | Nicolaus Necansus, O.F.M. † | Bishop of Mostar, Bosnia and Herzegovina |
| 24 Jun | | Ordained Bishop | Orazio Giraldi † | Bishop of Comacchio, Italy |
| 25 Jun | | Died | Alfonso de la Cerda, O.P. † | Bishop of Coro, Venezuela |
| Died | Alfonso de Lacerda, O.P. † | Bishop of La Plata o Charcas, Bolivia |