| Date | Age | Event | Bishop | Title | Current Title |
| unknown | | Died | Giovan Mario de Alessandris † | Bishop of Mileto, Italy |
| Born | Giovanni Battista Astalli † | | Bishop of Troia, Italy |
| Born | Augustinus Basrci (Bagesius), O.P. † | Albanen | Archbishop of Nachitschewan (Naxivan, Nakhtchevan, Nakhchivan), Armenia |
| Resigned | Paolo Bellardito † | Bishop of Lipari, Italy | Bishop Emeritus |
| Appointed | Martin Brenner † | Bishop of Seckau, Austria |
| Born | Celestino Bruni, O.S.A. † | Venusii | Bishop of Boiano, Italy |
| 63.0 | Appointed | Afonso de Castelo-Branco † | Bishop of Coimbra, Portugal |
| Born | Cristoforo Caetani † | | Bishop of Foligno, Italy |
| Born | Domenico Campanella, O. Carm. † | Putigliano | Bishop of Sant’Agata de’ Goti, Italy |
| Died | Nunzio Antonio de Capriolis † | Bishop of Tricarico, Italy |
| Born | Francesco Cherubini † | Montalboddo | Cardinal, Bishop of Senigallia, Italy |
| Resigned | William Chisholm † | Administrator of Vaison, France | Former Administrator |
| Resigned | Angelo di Cipro, O.P. † | Bishop of Santorini {Thira}, Greece | Bishop Emeritus |
| Died | Pedro Coderos † | Archbishop of Otranto, Italy |
| Died | Vincenzo de Doncelli (Donzelli), O.P. † | Bishop of Valva, Italy |
| Born | Lelio Falconieri † | Florence, Italy | Cardinal, Secretary of the Congregation of Bishops and Regulars |
| 60.7 | Resigned | Pietro Fauno Costacciaro † | Bishop of Acqui, Italy | Bishop of Vigevano, Italy |
| Born | Guillaume Fouquet de la Varenne † | | Bishop of Angers, France |
| Born | Bartolomeo Frigerio † | Ferrariae | Bishop of Venosa, Italy |
| Died | Paolo Giovio (il Giovane) † | Bishop of Nocera de’ Pagani, Italy |
| Born | Bartolomeo Giustiniani † | Chien | Bishop of Avellino e Frigento, Italy |
| Born | Bartolomé González Soltero † | México | Bishop of Guatemala (Santiago de Guatemala), Guatemala |
| Died | Basilio Gradi, O.S.B. † | Bishop of Stagno (Ston), Croatia |
| Died | Alfonso Graniero Avalos † | Bishop of La Plata o Charcas, Bolivia |
| Resigned | Annibale Grassi † | Bishop of Faenza, Italy | Bishop Emeritus |
| Died | Giovanni Antonio Grignetta † | Bishop of San Marco (Argentano), Italy |
| Died | Francisco Guaresma, O.F.M. † | Bishop of Tanger, Morocco |
| Born | Cornelius Janssen † | Acquoi, Netherlands | Bishop of Ypres (Ieper), Belgium |
| Born | Fabio Lagonissa † | Napoli | Titular Patriarch of Antiochia {Antioch} |
| Died | Jorge de Lemos, O.P. † | Bishop Emeritus of Funchal, Portugal |
| Born | Martín de León Cárdenas, O.S.A. † | Archidona, Spain | Archbishop of Palermo, Italy |
| Born | Annibale Mascambruno † | Benevento | Bishop of Castellammare di Stabia, Italy |
| Born | Martinus Meurisse, O.F.M. † | | Auxiliary Bishop of Metz, France |
| Born | John O’Cullenan † | | Bishop of Raphoe, Ireland |
| Died | Paolo Odescalchi † | Bishop Emeritus of Penne e Atri, Italy |
| Born | Malachy O’Queely † | Drizza | Archbishop of Tuam, Ireland |
| Born | Ottavio Orsini † | | Bishop of Segni, Italy |
| Resigned | Fantino Petrignani † | Archbishop of Cosenza, Italy | Archbishop Emeritus |
| Died | Costantino Piccioni, O.S.A. † | Bishop of Cortona, Italy |
| Resigned | Giovanni Battista Pietralata † | Bishop of Sant’Angelo dei Lombardi e Bisaccia, Italy | Bishop Emeritus |
| Died | Adam Pilchowski † | Bishop of Chełm, Poland |
| Died | Tarquinio Prisco † | Bishop of Cariati e Cerenzia, Italy |
| Died | Alessandro Ravadio † | Bishop of Nicastro, Italy |
| Born | Christophorus Johannes Reinheld von Reichenau † | Reichenau | Prefect of Meißen (Meissen) {Lusazia o Lausitz; Sassonia}, Germany |
| Died | Sigismondo Saraceno † | Archbishop of Acerenza e Matera, Italy |
| Born | Alessandro (Fabrizio) Suardi † | Napoli | Bishop of Caserta, Italy |
| Born | Francisco Torres Grijalba, O.S.A. † | Madrid | Bishop of Mondoñedo, Spain |
| Died | Pedro Vélez Guevara † | Bishop of Ciudad Rodrigo, Spain |
| Jan | | Died | Cesare Contardo † | Bishop of Sagone (Sagona), France |
| 5 Jan | | Born | Carlo Emmanuele Pio di Savoia † | Ferrara, Italy | Cardinal, Cardinal-Bishop of Ostia (e Velletri) |
| 7 Jan | 23.7 | Appointed | Charles de Lorraine-Vaudémont (II) † | Bishop of Verdun, France | Cardinal, Apostolic Administrator of Toul, France |
| 13 Jan | | Ordained Bishop | Clément Graebbels (Crabeels) † | Bishop of ’s Hertogenbosch (Bois-le-Duc), Netherlands |
| Ordained Bishop | Scipione Gesualdo † | Archbishop of Conza, Italy |
| Ordained Bishop | Pierre Simons † | Bishop of Ypres (Ieper), Belgium |
| 14 Jan | | Appointed | Giovanni Luigi Marescotti † | Bishop of Strongoli, Italy |
| 49.9 | Installed | Niccolò Sfondrati † | Cardinal-Priest of Santa Cecilia | Pope (Roma {Rome}, Italy) |
| 53.8 | Installed | Agostino Valier (Valeri, Valieri) † | Cardinal-Priest of San Marco | Cardinal, Bishop of Verona, Italy |
| 23 Jan | | Appointed | Diego Haëdo † | Bishop of Agrigento (Girgenti), Italy | Archbishop of Palermo, Italy |
| Appointed | Antonio Lombardo † | Archbishop of Messina, Italy |
| 28 Jan | | Appointed | Diego Aponte Quiñones, O.S. † | Bishop of Oviedo, Spain | Bishop of Málaga, Spain |
| Appointed | Bernardo de Benedictis † | Bishop of Castellaneta, Italy |
| 38.8 | Confirmed | Anne d’Escars de Givry (de Pérusse), O.S.B. † | Bishop of Lisieux, France | Cardinal, Bishop of Metz, France |
| 31 Jan | | Died | Vincenzo Luchi (di Luca) † | Bishop of Ancona e Numana, Italy |
| 71.1 | Died | Benito Tocco, O.S.B. † | Bishop of Lérida, Spain |
| Feb | 46.6 | Resigned | Alberto Bolognetti † | Apostolic Nuncio to Poland | Cardinal, Bishop of Massa Marittima, Italy |
| 4 Feb | | Appointed | Domingo de Ulloa, O.P. † | Bishop of Nicaragua | Bishop of Michoacán, México |
| 11 Feb | 37.1 | Appointed | Wojciech Baranowski † | Bishop of Przemyśl, Poland | Archbishop of Gniezno, Poland |
| 24 Feb | 64.4 | Appointed | Alessandro Farnese (Jr.) † | Administrator of Ancona e Numana, Italy | Cardinal, Cardinal-Bishop of Ostia (e Velletri) |
| 25 Feb | | Appointed | Alfonso Herrera, O.S.A. † | Bishop of Ariano, Italy |
| 6 Mar | | Died | Giovanni Tommaso Sanfelice † | Bishop of Venosa, Italy |
| 12 Mar | | Ordained Bishop | Bernardo de Benedictis † | Bishop of Castellaneta, Italy |
| 18 Mar | | Appointed | Crisostomo Arameo, O.S.B. † | Bishop of Stagno (Ston), Croatia |
| Appointed | Gian Antonio Grassi † | Bishop of Faenza, Italy |
| 31 Mar | | Ordained Bishop | Diego Aponte Quiñones, O.S. † | Bishop of Oviedo, Spain | Bishop of Málaga, Spain |
| Ordained Bishop | Diego Haëdo † | Bishop of Agrigento (Girgenti), Italy | Archbishop of Palermo, Italy |
| 3 Apr | 84.3 | Died | Thomas Goldwell, C.R. † | Bishop of Saint Asaph, Wales, Great Britain |
| 10 Apr | 83.3 | Died | Ugo Boncompagni † | Pope (Roma {Rome}, Italy) |
| 24 Apr | 63.4 | Elected | Felice Peretti Montalto, O.F.M. Conv. † | Pope (Roma {Rome}, Italy) |
| 25 Apr | | Born | Diego Arce Reinoso † | Zalamea de la Serena | Bishop Emeritus of Plasencia, Spain |
| May | | Born | Giovanni Pietro Volpi † | Como | Bishop of Novara, Italy |
| 1 May | 39.1 | Ordained Bishop | Anne d’Escars de Givry (de Pérusse), O.S.B. † | Bishop of Lisieux, France | Cardinal, Bishop of Metz, France |
| 63.4 | Installed | Felice Peretti Montalto, O.F.M. Conv. † | Pope (Roma {Rome}, Italy) |
| 59.2 | Died | Niccolò Caetani di Sermoneta † | Cardinal, Archbishop of Capua, Italy |
| 3 May | 34.5 | Died | Heinrich von Sachsen-Lauenburg † | Archbishop-Elect of Bremen (and Hamberg), Germany |
| 10 May | 35.8 | Appointed | Ferdinando de’ Medici † | Cardinal-Deacon of Sant’Eustachio | |
| Appointed | Marco Antonio del Tufo † | Bishop of San Marco (Argentano), Italy | Bishop of Mileto, Italy |
| 13 May | | Appointed | Francesco Carusi, O.F.M. Conv. † | Bishop of Valva, Italy |
| Appointed | Francesco Carusi, O.F.M. Conv. † | Bishop of Sulmona, Italy | Bishop of Valva, Italy |
| 14.4 | Elevated to Cardinal | Alessandro Damasceni Peretti † | Cardinal, Cardinal-Bishop of Albano |
| Appointed | Marino Querini † | Bishop of Concordia (Sagittaria), Italy |
| 16 May | 48.0 | Died | Guido Luca Ferrero † | Cardinal, Bishop Emeritus of Vercelli, Italy |
| 17 May | 46.9 | Died | Alberto Bolognetti † | Cardinal, Bishop of Massa Marittima, Italy |
| 18 May | 30.4 | Selected | Ernst von Bayern † | Bishop of Münster, Germany | Archbishop-Elect of Köln {Cologne}, Germany |
| Died | François de La Valette † | Bishop of Vabres, France |
| 23.0 | Resigned | Johann Wilhelm von Jülich-Kleve-Berg † | Bishop-Elect of Münster, Germany | Former Bishop-Elect |
| 19 May | 57.6 | Died | Tomás Dacio (d’Anio) † | Bishop of Orihuela, Spain |
| 20 May | 62.2 | Installed | Rodrigo de Castro Osorio (de Lemos) † | Cardinal-Priest of Santi XII Apostoli | Cardinal, Archbishop of Sevilla {Seville}, Spain |
| 22.9 | Installed | François de Joyeuse † | Cardinal-Priest of San Silvestro in Capite | Cardinal, Archbishop of Rouen, France |
| 62.2 | Installed | Vincenzo Lauro † | Cardinal-Priest of Santa Maria in Via | Cardinal, Bishop Emeritus of Mondovi, Italy |
| Appointed | Giovanni Gerolamo Mareri † | Bishop of Venosa, Italy |
| Appointed | Silvio Passerini † | Archbishop of Cosenza, Italy |
| 35.0 | Installed | Simeone Tagliavia d’Aragonia † | Cardinal-Deacon of Santa Maria degli Angeli | Cardinal, Cardinal-Bishop of Sabina |
| 23 May | | Died | Marcin Gerstmann † | Bishop of Wrocław (Breslau), Poland |
| 3 Jun | | Appointed | Jerónimo Barreto † | Bishop of Faro {Algarve}, Portugal |
| 5 Jun | 38.7 | Selected | Dietrich von Fürstenberg † | Bishop of Paderborn, Germany |
| 10 Jun | | Died | Girolamo Diedo † | Bishop Emeritus of Crema, Italy |
| 14 Jun | 14.5 | Installed | Alessandro Damasceni Peretti † | Cardinal-Deacon of San Girolamo dei Croati | Cardinal, Cardinal-Bishop of Albano |
| 17 Jun | | Died | Fernando Rueda † | Bishop of Islas Canarias {Canary Islands}, Spain |
| 24 Jun | 24.2 | Installed | Charles de Lorraine-Vaudémont (II) † | Cardinal-Deacon of Santa Maria in Domnica | Cardinal, Apostolic Administrator of Toul, France |
| 25 Jun | | Died | Cesare Gromis † | Bishop of Aosta, Italy |
| 28 Jun | 70.5 | Died | Felipe Urríes Urríes, O.P. † | Bishop of Barbastro, Spain |