| Date | Age | Event | Bishop | Title | Current Title |
| unknown | | Born | Manuel Baptista, O.F.M. † | Monção, Portugal | Bishop of Angola e Congo, Angola |
| Born | Ottavio Belmosto (Belmusti) † | Genoa, Italy | Cardinal, Bishop Emeritus of Aleria, France |
| 17.1 | Professed | Michele (Bosco) Bonelli, O.P. † | Member of Order of Friars Preachers | Cardinal, Cardinal-Bishop of Albano |
| 59.0 | Resigned | Edmund Bonner † | Bishop of London, England, Great Britain | Bishop Emeritus |
| 35.8 | Ordained Priest | Rodrigo de Castro Osorio (de Lemos) † | Priest of Cuenca, Spain | Cardinal, Archbishop of Sevilla {Seville}, Spain |
| Died | Rodrigo de Carvalho † | Bishop of Miranda (de Duero), Portugal |
| Resigned | Bernardino della Croce, B. † | Bishop of Como, Italy | Bishop Emeritus |
| Born | François de Donadieu † | | Bishop of Auxerre, France |
| 40.0 | Appointed | Philippe du Bec † | Bishop of Vannes, France | Archbishop of Reims, France |
| Died | Jan Dzieduski † | Bishop of Przemyśl, Poland |
| Died | Francesco Franchini † | Bishop of Massa Marittima, Italy |
| Born | Francisco González de Salcedo Castro † | Ciudad Real, Spain | Bishop of Santiago de Chile |
| Died | Jean-Philippe de Groslée † | Archbishop of Tarentaise (Moûtiers-en-Tarentaise), France |
| 58.0 | Resigned | Nicholas Heath † | Archbishop of York, England, Great Britain | Archbishop Emeritus |
| Ordained Priest | Wolfgang Holl † | Priest of Eichstätt, Germany | Auxiliary Bishop |
| 52.0 | Ordained Priest | Honorato Juan † | Priest | Bishop of Osma, Spain |
| Born | Karel Maes † | | Bishop of Gent {Ghent, Gand}, Belgium |
| Died | Jaime Martínez Casanat, O. Carm. † | Auxiliary Bishop of Zaragoza, Spain |
| Died | Eugene MacBrehon, O. Carm. † | Bishop of Mayo, Ireland |
| Born | Johann Jakob Mirgel † | Lindau | Auxiliary Bishop of Konstanz {Constance}, Germany |
| Born | Lorenzo Nieto y Corrales Montero Nieto, O.S.B. † | Orgaz | Archbishop of Cagliari, Italy |
| Born | Vincenzo Querini † | | Archbishop of Corfù, Greece |
| Born | Melchor Rodríguez de Torres, O. de M. † | Burgos | Auxiliary Bishop of Burgos, Spain |
| 76.8 | Died | Tomás de San Martín, O.P. † | Bishop of La Plata o Charcas, Bolivia |
| Resigned | Gianfrancesco Sanseverino † | Bishop of Acerra, Italy | Bishop Emeritus |
| Died | Girolamo Sauli † | Archbishop of Genova, Italy |
| Appointed | Giulio (Egidio) Soperchio † | Bishop of Acci (Accia), France | Bishop of Caorle, Italy |
| 56.0 | Selected | Frederik Schenck van Toutenburg † | Archbishop of Utrecht, Netherlands |
| Died | Catalano Trivulzio † | Bishop of Piacenza, Italy |
| Born | Ulpiano (Volpiano) Volpi † | Como | Bishop of Novara, Italy |
| 8 Jan | | Died | Sebastián Obregón, O.S.B. † | Auxiliary Bishop of Sevilla {Seville}, Spain |
| 18 Jan | 17.4 | Died | Roberto de’ Nobili † | Cardinal, Cardinal-Deacon of S. Maria in Domnica |
| 23 Jan | | Appointed | Pedro Maldonado, O.F.M. † | Bishop of Mondoñedo, Spain |
| Confirmed | Burchard Oberg † | Bishop of Hildesheim, Germany |
| 25 Jan | | Born | Aleixo de Meneses, O.S.A. † | Lisbonne | Archbishop of Braga, Portugal |
| 27 Jan | 44.7 | Confirmed | Bl. Bartolomé Fernandes dos Mártires, O.P. † | Archbishop of Braga, Portugal | Archbishop Emeritus |
| Appointed | Sebastiano Antonio Minturno † | Bishop of Ugento, Italy | Bishop of Crotone (Cotrone), Italy |
| Feb | 40.1 | Ordained Bishop | Pedro Leitão † | Bishop of São Salvador da Bahia, Brazil |
| 15 Feb | 67.1 | Appointed | Jean du Bellay † | Administrator of Bordeaux, France | Cardinal, Bishop Emeritus of Paris, France |
| Appointed | Marco Grimani † | Bishop of Tinos, Greece |
| 22 Feb | | Died | Mikołaj Dzierzgowski † | Archbishop of Gniezno, Poland |
| Succeeded | Jan Przerębski † | Archbishop of Gniezno, Poland |
| 6 Mar | 18.6 | Appointed | Alfonso Carafa † | Cardinal-Deacon of S. Maria in Domnica | Cardinal, Archbishop of Napoli {Naples}, Italy |
| 28.2 | Appointed | Vitellozzo Vitelli † | Cardinal-Deacon of S. Maria in Portico (Octaviae) | Cardinal, Bishop Emeritus of Città di Castello, Italy |
| 13 Mar | 56.1 | Died | Johann Gropper † | Cardinal, Cardinal-Deacon of S. Lucia in Orphea |
| 15 Mar | | Appointed | Francisco Orozco de Arce † | Archbishop of Palermo, Italy |
| 26 Mar | | Born | Wolf Dietrich von Raitenau † | Lochau | Archbishop Emeritus of Salzburg, Austria |
| 8 Apr | | Died | Leo Lösch von Hilkershausen † | Bishop of Freising, Germany |
| 17 Apr | | Succeeded | Filippo Maria Campeggi † | Bishop of Feltre, Italy |
| Resigned | Tomaso Campeggi † | Bishop of Feltre, Italy | Bishop Emeritus |
| Appointed | Agostino Maria Salvago, O.P. † | Archbishop of Genova, Italy |
| Appointed | Gianantonio Volpi † | Bishop of Como, Italy |
| 27 Apr | 53.3 | Died | Gutierre Vargas de Carvajal † | Bishop of Plasencia, Spain |
| 22 May | 60.4 | Died | Virgilio Rosario † | Cardinal, Bishop of Ischia, Italy |
| 12 Jun | | Selected | Moritz von Sandizell † | Bishop of Freising, Germany | Bishop Emeritus |
| 17 Jun | | Died | Bartolomeo Pipero † | Bishop of Mondovi, Italy |
| 21 Jun | 55.5 | Resigned | Ralph Baines † | Bishop of Coventry and Lichfield, England, Great Britain | Bishop Emeritus |
| 25 Jun | 45.5 | Died | Antonio Trivulzio (Jr.) † | Cardinal, Bishop of Toulon, France |
| 2 Jul | | Ordained Bishop | Francisco Orozco de Arce † | Archbishop of Palermo, Italy |
| 5 Jul | 59.5 | Resigned | Thomas Thirlby † | Bishop of Ely, England, Great Britain | Bishop Emeritus |
| 2 Aug | | Appointed | Diego de los Cobos Molina † | Bishop of Avila, Spain | Bishop of Jaén, Spain |
| 54.6 | Appointed | Juan Quiñones Guzmán † | Bishop of Calahorra y La Calzada, Spain |
| 5 Aug | | Born | Wawrzyniec Gembicki † | | Archbishop of Gniezno, Poland |
| 9 Aug | 66.6 | Appointed | Gianbernardino Scotti, C.R. † | Archbishop (Personal Title) of Piacenza, Italy | Cardinal, Bishop Emeritus |
| 11 Aug | 56.6 | Selected | Johannes Tiedemann † | Bishop of Lübeck, Germany | Bishop-Elect |
| 15 Aug | 59.6 | Died | Luigi Lippomano † | Bishop of Bergamo, Italy |
| 16 Aug | 30.6 | Selected | Marquard von Hattstein † | Coadjutor Bishop of Speyer, Germany | Bishop |
| 18 Aug | 83.1 | Died | Gian Pietro Carafa † | Pope (Roma {Rome}, Italy) |
| 22 Aug | 32.3 | Selected | Johann Leisentrit † | Prefect of Meissen (Meißen) {Lusazia o Lausitz; Sassonia}, Germany |
| 25 Aug | 68.6 | Died | Giovanni Battista Consiglieri † | Cardinal, Cardinal-Deacon of S. Nicola in Carcere |
| Sep | | Died | Juan Fonseca † | Bishop of Castellammare di Stabia, Italy |
| 3 Sep | 45.3 | Ordained Bishop | Bl. Bartolomé Fernandes dos Mártires, O.P. † | Archbishop of Braga, Portugal | Archbishop Emeritus |
| 26 Sep | 55.7 | Died | Georg (Joris) van Egmond † | Bishop of Utrecht, Netherlands |
| Born | Claudio Rangoni † | Modena | Bishop of Reggio Emilia, Italy |
| 4 Oct | 45.4 | Installed | Bl. Bartolomé Fernandes dos Mártires, O.P. † | Archbishop of Braga, Portugal | Archbishop Emeritus |
| 8 Oct | | Died | Vincenzo Diedo † | Patriarch of Venezia {Venice}, Italy |
| 11 Nov | | Born | Albrecht von Austria (Österreich) † | Wiener Neustadt | Former Archbishop-Elect of Toledo, Spain |
| 18 Nov | 55.9 | Died | Ralph Baines † | Bishop Emeritus of Coventry and Lichfield, England, Great Britain |
| 85.9 | Died | Cuthbert Tunstall † | Bishop Emeritus of Durham, England, Great Britain |
| 21 Nov | | Died | Miguel Puig † | Bishop of Lérida, Spain |
| 25 Nov | | Died | Cristoforo de Nigris † | Bishop of Trogir (Traù), Croatia |
| 66.9 | Died | Antoine Sanguin de Meudon † | Cardinal, Bishop Emeritus of Orléans, France |
| 1 Dec | 57.4 | Died | Girolamo Recanati Capodiferro † | Bishop of Saint-Jean-de-Maurienne, France | Cardinal, Bishop of Nice, France |
| 4 Dec | 50.9 | Died | Girolamo Dandini † | Cardinal, Bishop Emeritus of Imola, Italy |
| 9 Dec | 40.9 | Installed | Pedro Leitão † | Bishop of São Salvador da Bahia, Brazil |
| 19 Dec | | Died | Francesco da Galliano † | Bishop of Pistoia, Italy |
| 21 Dec | | Died | Ghillino Ghillini † | Bishop of Comacchio, Italy |
| Succeeded | Alfonso Rossetti † | Bishop of Comacchio, Italy | Bishop of Ferrara, Italy |
| 25 Dec | 60.7 | Elected | Giovanni Angelo de’ Medici † | Pope (Roma {Rome}, Italy) |
| 29 Dec | | Born | Gonzalo de Salazar, O.S.A. † | México | Bishop of Yucatán (Mérida), México |