| Date | Age | Event | Bishop | Title | Current Title |
| unknown | | Appointed | James Beaton † | Archbishop of Saint Andrews, Scotland, Great Britain |
| Died | Ottonis Boynstruet † | Bishop of Västerås, Sweden |
| Ordained Priest | Anton Braun † | Priest of Eichstätt, Germany | Auxiliary Bishop |
| Born | Afonso de Castelo-Branco † | | Bishop of Coimbra, Portugal |
| Died | Pedro Cardona, C.R.S.A. † | Bishop of Shkodrë (Scutari), Albania |
| Died | Bonifacio Catagnano † | Bishop of Malta |
| Born | Pierdonato Cesi (Sr.) † | Rome | Cardinal, Cardinal-Priest of Sant’Anastasia |
| Died | Andrea Cibo (Cybo) † | Bishop of Terracina, Priverno e Sezze, Italy |
| Appointed | Giovanni de Copis † | Bishop of Terracina, Priverno e Sezze, Italy |
| Died | Massimo Bruni Corvino † | Bishop of Isernia, Italy |
| Died | Gavin Douglas † | Bishop of Dunkeld, Scotland, Great Britain |
| Appointed | Artur Fillon † | Bishop of Senlis, France |
| Born | Juan de Liermo Hermosa † | San Martín de Liermo | Archbishop of Santiago de Compostela, Spain |
| Died | Konrad Mair † | Auxiliary Bishop of Freising, Germany |
| Died | Corrado Manili † | Bishop of Bagnoregio (Bagnorea), Italy |
| Appointed | Erasmus Manteuffel † | Bishop of Kammin (Camin), Germany |
| Died | Gaspart de Montpezat † | Bishop of Rieux, France |
| Died | Benedetto Paganotti, O.P. † | Bishop of Vaison, France |
| Resigned | Guillaume de Pélissier, O.S.A. † | Bishop of Orange, France | Bishop Emeritus |
| Born | Luigi Pisani † | Venice | Cardinal, Bishop of Padova {Padua}, Italy |
| Died | Camillo Porzj † | Bishop of Teramo, Italy |
| Died | García de Quijada, O.F.M. † | Bishop of Guadix, Spain |
| Died | Pedro Ruiz de la Mota, O.S.B. † | Bishop of Palencia, Spain |
| Born | Girolamo Simoncelli † | Orvieto, Italy | Cardinal, Cardinal-Bishop of Porto e Santa Rufina |
| Resigned | Piotr Tomicki † | Bishop of Poznań, Poland | Bishop of Kraków, Poland |
| Appointed | Charles de Villiers de L’Isle-Adam † | Bishop of Limoges, France | Bishop of Beauvais, France |
| 1 Jan | 29.0 | Appointed | Giovanni Domenico de Cupis † | Administrator of Recanati, Italy | Cardinal, Cardinal-Bishop of Ostia (e Velletri) |
| 5 Jan | | Born | Giovanni Carlo Bovio † | Brindisi | Archbishop of Brindisi, Italy |
| 7 Jan | 23.7 | Appointed | Jean de Lorraine † | Administrator of Thérouanne, France | Cardinal, Bishop of Metz, France |
| 9 Jan | 62.9 | Elected | Adriaan Florenszoom Dedel † | Pope (Roma {Rome}, Italy) |
| 15 Jan | | Died | Richard FitzJames † | Bishop of London, England, Great Britain |
| 2 Feb | | Born | Francesco Alciati † | Milan | Cardinal, Bishop of Civitate (Città or Civita), Italy |
| 11 Mar | 54.2 | Resigned | Matthäus Lang von Wellenburg † | Bishop of Gurk, Austria | Cardinal, Archbishop of Salzburg, Austria |
| 22 Mar | | Born | Daniel Brendel von Homburg † | Aschaffenburg | Archbishop of Mainz, Germany |
| 15 Apr | | Died | Galeotto Graziani, O. Camald. † | Bishop of Sansepolcro (Borgo San Sepolcro), Italy |
| 16 Apr | 28.3 | Appointed | Leonardo Tornabuoni † | Bishop of Sansepolcro (Borgo San Sepolcro), Italy | Bishop of Ajaccio, France |
| 26 Apr | | Died | Georg von Slatkonia † | Bishop of Wien, Austria |
| 28 Apr | 47.3 | Appointed | Juan de Witte Hoos (Ubite), O.P. † | Bishop of Santiago de Cuba | Bishop Emeritus of Santiago de Cuba |
| 31 May | 52.4 | Died | Georg Schenk von Limpurg † | Bishop of Bamberg, Germany |
| 15 Jun | | Ordained Bishop | Ricomanni Buffalini † | Bishop of Venafro, Italy |
| 18 Jun | 46.5 | Selected | Weigand von Redwitz † | Bishop of Bamberg, Germany |
| 19 Jun | | Appointed | Andreas Mozenicus † | Bishop of Bitetto, France | Bishop of Nemosia (Limasol), Greece |
| 9 Jul | | Ordained Bishop | Artur Fillon † | Bishop of Senlis, France |
| 23 Aug | | Died | Juan Castellanos de Villalba † | Bishop of Calahorra y La Calzada, Spain |
| 31 Aug | 63.5 | Installed | Adriaan Florenszoom Dedel † | Pope (Roma {Rome}, Italy) |
| 4 Sep | 58.8 | Appointed | Andrea Della Valle † | Bishop of Crotone (Cotrone), Italy | Cardinal, Cardinal-Bishop of Palestrina |
| 7 Sep | | Appointed | Francesco Cherigatto † | Bishop of Teramo, Italy |
| 9 Sep | 48.7 | Died | Erazm Ciołek † | Bishop of Płock, Poland |
| 10 Sep | 58.8 | Resigned | Andrea Della Valle † | Administrator of Umbriatico (Umbriaticum), Italy | Cardinal, Cardinal-Bishop of Palestrina |
| Appointed | Giovanni Matteo Lucifero † | Bishop of Umbriatico (Umbriaticum), Italy | Bishop of Crotone (Cotrone), Italy |
| 64.1 | Appointed | Lorenzo Pucci † | Administrator of Capaccio, Italy | Cardinal, Cardinal-Bishop of Palestrina |
| 48.7 | Appointed | Cuthbert Tunstall † | Bishop of London, England, Great Britain | Bishop Emeritus of Durham, England, Great Britain |
| 26 Sep | 54.7 | Selected | Busso von Alvensleben † | Coadjutor Bishop of Havelberg, Germany | Bishop |
| 44.3 | Resigned | Giulio de’ Medici † | Administrator of Worcester, England, Great Britain | Pope (Roma {Rome}, Italy) |
| 42.7 | Appointed | Girolamo Ghinucci {Ginucci} † | Cardinal, Bishop of Worcester, England, Great Britain |
| 37.7 | Appointed | Agostino Trivulzio † | Administrator of Bobbio, Italy | Cardinal, Cardinal-Deacon of Sant’Adriano al Foro |
| 30 Sep | 57.7 | Died | Matthäus Schinner † | Cardinal, Bishop of Sion {Sitten}, Switzerland |
| 4 Oct | | Born | Gabriele Paleotti † | Bologna | Cardinal, Archbishop of Bologna, Italy |
| 10 Oct | 45.8 | Appointed | Pierre de La Baume † | Bishop of Genève {Geneva}, Switzerland | Cardinal, Archbishop Emeritus of Besançon, France |
| 19 Oct | 48.8 | Ordained Bishop | Cuthbert Tunstall † | Bishop of London, England, Great Britain | Bishop Emeritus of Durham, England, Great Britain |
| 20 Oct | 50.8 | Died | Erich von Sachsen-Lauenburg † | Bishop of Münster, Germany |
| 29 Oct | 54.8 | Succeeded | Busso von Alvensleben † | Bishop of Havelberg, Germany |
| Died | Hieronymus Schultz, O. Praem. † | Bishop of Havelberg, Germany |
| Nov | | Died | Ottobono Fieschi † | Bishop of Mondovi, Italy |
| Died | Edward Vaughan † | Bishop of Saint David’s, Wales, Great Britain |
| 6 Nov | 44.8 | Selected | Friedrich zu Wied † | Bishop of Münster, Germany | Former Bishop-Elect |
| 10 Nov | 54.9 | Ordained Bishop | Busso von Alvensleben † | Bishop of Havelberg, Germany |
| 12 Nov | 41.9 | Appointed | Paolo Emilio Cesi † | Administrator of Sion {Sitten}, Switzerland | Cardinal, Cardinal-Deacon of Sant’Eustachio |
| 28 Nov | 57.9 | Died | Erik Valkendorf † | Archbishop of Nidaros (Trondheim), Norway |
| 10 Dec | | Appointed | Ugo de Spina † | Bishop of Bagnoregio (Bagnorea), Italy |
| 11 Dec | 50.9 | Died | Raffaello Petrucci † | Cardinal, Bishop of Grosseto, Italy |
| 17 Dec | | Appointed | Louis de Pélissier, O.S.A. † | Bishop of Orange, France |
| 22 Dec | | Appointed | Jean Dupin (de Pins) † | Bishop of Rieux, France |
| 79.0 | Appointed | Ferdinando Ponzetti (Poncetti) † | Bishop of Grosseto, Italy | Cardinal, Bishop Emeritus |