| Date | Age | Event | Bishop | Title | Current Title |
|---|---|---|---|---|---|
| unknown | Died | Gerolamo Acciabianca † | Bishop of Nusco, Italy | ||
| Resigned | Lópe Alarcón † | Bishop of Bitonto, Italy | Bishop Emeritus | ||
| 43.0 | Appointed | David Beaton † | Coadjutor Archbishop of Saint Andrews, Scotland, Great Britain | Cardinal, Archbishop | |
| Died | Silvestro Benedetti † | Bishop of Luni e Sarzana, Italy | |||
| 51.0 | Resigned | Tomás de Berlanga, O.P. † | Bishop of Panamá | Bishop Emeritus | |
| Died | Vincenzo Boccaferro, O.S.B. † | Bishop of Marsico Nuovo, Italy | |||
| Died | Galcerán Cassanyach, O. Carm. † | Auxiliary Bishop of Mallorca, Spain | |||
| Died | Bartolomeo Cesi † | Bishop of Narni, Italy | |||
| Died | Francesco di Créqui † | Bishop of Thérouanne, France | |||
| Resigned | Andrea Cornaro † | Archbishop of Split (Spalato), Croatia | Archbishop Emeritus | ||
| Died | Guido de’ Medici † | Archbishop of Chieti, Italy | |||
| Appointed | Lélio des Ursins de Céri † | Bishop of Lodève, France | |||
| Died | Simeone de’ Vernacoli † | Bishop of Pozzuoli, Italy | |||
| Born | Ippolito Fabiani, O.S.A. † | Bishop of Civita Castellana e Orte, Italy | |||
| 16.2 | Appointed | Alessandro Farnese (Jr.) † | Archpriest of the Basilica di Santa Maria Maggiore {Saint Mary Major Basilica} | Cardinal, Cardinal-Bishop of Ostia (e Velletri) | |
| Died | Vito Ferrato † | Bishop of Mottola (Motula), Italy | |||
| Resigned | Gaspar Flores † | Auxiliary Bishop of Sigüenza, Spain | Bishop of Foreign Diocese | ||
| Born | Giovanni Fontana † | Vignola | Bishop of Ferrara, Italy | ||
| Died | Bernardo Gentile, O.P. † | Bishop of Bosa, Italy | |||
| Born | Melchior Giedroyc † | Bishop of Žemaičiai (Samogizia o Tels; Żmudź), Lithuania | |||
| 49.0 | Resigned | Marino Grimani † | Administrator of Concordia (Sagittaria), Italy | Cardinal, Titular Patriarch of Constantinople | |
| Died | Antonio La Legname † | Archbishop of Messina, Italy | |||
| Ordained Bishop | Miguel Maigues, O.S.A. † | Auxiliary Bishop of Segovia, Spain | Bishop of Ales e Terralba, Italy | ||
| Born | Gianfrancesco Morosini † | Venice | Cardinal, Bishop of Brescia, Italy | ||
| Died | Angelo Pappacoda † | Bishop of Martirano (Martoranum), Italy | |||
| Resigned | Giacomo Pellegrini † | Bishop of Fondi (Fundi), Italy | Bishop Emeritus | ||
| Died | Pietro Petrucci † | Bishop of Bertinoro, Italy | |||
| Born | Lorenzo Priuli † | Venice | Cardinal, Patriarch of Venezia {Venice}, Italy | ||
| Died | Giannotto Pucci † | Bishop of Melfi e Rapolla, Italy | |||
| Born | Gerolamo Ragazzoni † | Venezia | Bishop of Bergamo, Italy | ||
| 77.1 | Died | Diego Ramírez de Fuenleal † | Bishop of Cuenca, Spain | ||
| Died | Jaime de Rich, O.S.B. † | Bishop of Elne, France | |||
| Resigned | Zaccaria Trevisani † | Bishop of Hvar (Lesina), Croatia | Bishop Emeritus | ||
| Died | Michele Zono † | Bishop of Kisamos, Greece | |||
| Jan | Born | Girolamo Rusticucci † | Cartoceto | Cardinal, Cardinal-Bishop of Porto e Santa Rufina | |
| 8 Jan | 69.0 | Resigned | Marino Ascanio Caracciolo † | Bishop of Catania, Italy | Cardinal, Bishop Emeritus |
| Appointed | Nicola Maria Caracciolo † | Bishop of Catania, Italy | |||
| Appointed | René Le Roullié † | Bishop of Senlis, France | |||
| 38.0 | Appointed | Vicente Valverde Alvarez, O.P. † | Bishop of Cuzco, Peru | ||
| 15 Jan | 13.0 | Appointed | Rodrigo Luis de Borja y de Castro-Pinós † | Cardinal, Cardinal-Deacon of San Nicola in Carcere | |
| 60.5 | Appointed | Gian Pietro Carafa † | Cardinal-Priest of San Pancrazio | Pope (Roma {Rome}, Italy) | |
| 49.3 | Appointed | Giovanni Maria Ciocchi del Monte † | Cardinal-Priest of San Vitale | Pope (Roma {Rome}, Italy) | |
| 53.2 | Appointed | Gasparo Contarini † | Cardinal-Priest of Santa Balbina | Cardinal, Bishop of Belluno, Italy | |
| 71.0 | Appointed | Ennio Filonardi † | Cardinal-Priest of Sant’Angelo in Pescheria | Cardinal, Administrator of Montefeltro, Italy | |
| Appointed | Cristoforo Giacobazzi † | Cardinal-Priest of Sant’Anastasia | Cardinal, Bishop of Cassano all’Jonio, Italy | ||
| 44.0 | Appointed | Charles de Hémard de Denonville † | Cardinal-Priest of San Matteo in Merulana | Cardinal, Bishop of Mâcon, France | |
| 36.9 | Appointed | Reginald Pole † | Cardinal-Deacon of Santi Nereo ed Achilleo | Cardinal, Archbishop of Canterbury, England, Great Britain | |
| 59.5 | Appointed | Jacopo Sadoleto † | Cardinal-Priest of San Callisto | Cardinal, Bishop of Carpentras, France | |
| 20 Jan | 43.4 | Died | Andrea Matteo Palmieri † | Cardinal, Administrator of Policastro, Italy | |
| 21 Jan | Born | Antonmaria Salviati † | Florence | Cardinal, Bishop Emeritus of Saint-Papoul, France | |
| 25 Jan | 57.1 | Appointed | Girolamo Ghinucci {Ginucci} † | Cardinal-Priest of San Clemente | Cardinal, Bishop of Worcester, England, Great Britain |
| 26 Jan | Appointed | Nicolás de Aragón † | Bishop of Bosa, Italy | ||
| Appointed | Johannes Bischopinck † | Auxiliary Bishop of Münster, Germany | |||
| 31 Jan | Appointed | Pedro Flores † | Bishop of Gaeta, Italy | ||
| Feb | Died | George de Athequa, O.P. † | Bishop of Llandaff, Wales, Great Britain | ||
| 7 Feb | 47.1 | Appointed | Giovanni Vincenzo Acquaviva d’Aragona † | Cardinal, Bishop of Melfi e Rapolla, Italy | |
| 12 Feb | Died | Pedro González Manso † | Bishop of Osma, Spain | ||
| 26 Feb | Appointed | Jean Lunel, O. Cist. † | Auxiliary Bishop of Bayeux, France | Auxiliary Bishop of Chartres, France | |
| Appointed | Jean Lunel, O. Cist. † | Titular Bishop of Sebaste in Cilicia | Auxiliary Bishop of Chartres, France | ||
| 5 Mar | Appointed | Fabrizio Arcella † | Bishop of Policastro, Italy | Bishop Emeritus | |
| Appointed | Berardo Bongiovanni † | Bishop of Camerino, Italy | |||
| 44.2 | Resigned | Giovanni Domenico de Cupis † | Administrator of Camerino, Italy | Cardinal, Cardinal-Bishop of Ostia (e Velletri) | |
| 11.0 | Appointed | Niccolò Caetani di Sermoneta † | Administrator of Bisignano, Italy | Cardinal, Archbishop of Capua, Italy | |
| 6 Mar | Appointed | Angelo Pasquali, O.P. † | Bishop of Mottola (Motula), Italy | ||
| 14 Mar | Appointed | Giovanni Angelo Pellegrini † | Bishop of Fondi (Fundi), Italy | Bishop of Gravina (di Puglia), Italy | |
| 2 Apr | Ordained Bishop | Nicolás de Aragón † | Bishop of Bosa, Italy | ||
| 8 Apr | 46.8 | Ordained Bishop | Juan Lopez de Zárate † | Bishop of Antequera, Oaxaca, México | |
| 59.3 | Ordained Bishop | Francisco Marroquin Hurtado † | Bishop of Guatemala (Santiago de Guatemala), Guatemala | ||
| 11 Apr | 48.7 | Appointed | Juan Álvarez de Toledo, O.P. † | Bishop of Burgos, Spain | Cardinal, Archbishop of Santiago de Compostela, Spain |
| 57.3 | Appointed | Antonio del Aguila Vela y Paz † | Bishop of Guadix, Spain | Bishop of Zamora, Spain | |
| Appointed | João de Albuquerque, O.F.M. † | Bishop of Goa, India | |||
| 44.3 | Resigned | Giovanni Domenico de Cupis † | Administrator of Montepeloso, Italy | Cardinal, Cardinal-Bishop of Ostia (e Velletri) | |
| 37.3 | Appointed | Pedro Fernández Manrique † | Cardinal, Bishop of Córdoba, Spain | ||
| Appointed | Agostino Gonzaga † | Archbishop of Reggio Calabria, Italy | |||
| Appointed | Antonio Guevara Noroña, O.F.M. † | Bishop of Mondoñedo, Spain | |||
| 48.8 | Appointed | Pedro Pacheco de Villena (Ladrón de Guevara) † | Bishop of Ciudad Rodrigo, Spain | Cardinal, Bishop of Sigüenza, Spain | |
| Appointed | Pietro Querini † | Bishop of Concordia (Sagittaria), Italy | |||
| 14 Apr | Appointed | Luis Cabeza de Vaca † | Bishop of Palencia, Spain | ||
| 17 Apr | Died | Antoine Dubois † | Bishop of Béziers, France | ||
| 20 Apr | Appointed | Miguel de Sanguesa, O. Cist. † | Auxiliary Bishop of Tarazona, Spain | ||
| Appointed | Miguel de Sanguesa, O. Cist. † | Titular Bishop of Rhosus | Auxiliary Bishop of Tarazona, Spain | ||
| 27 Apr | Appointed | Juan Fonseca † | Bishop of Castellammare di Stabia, Italy | ||
| 1 May | Succeeded | Angelo Collocio † | Bishop of Nocera Umbra, Italy | Bishop Emeritus | |
| Died | Guarino Favorino, O.S.B. † | Bishop of Nocera Umbra, Italy | |||
| 3 May | Ordained Bishop | Miguel de Sanguesa, O. Cist. † | Titular Bishop of Rhosus | Auxiliary Bishop of Tarazona, Spain | |
| 10 May | Died | Andrzej Krzycki † | Archbishop of Gniezno, Poland | ||
| 18 May | Born | Guido Luca Ferrero † | Turin | Cardinal, Bishop Emeritus of Vercelli, Italy | |
| 28 May | 62.6 | Resigned | Lorenzo Campeggio † | Administrator of Poreč (Parenzo), Croatia | Cardinal, Cardinal-Bishop of Sabina |
| Appointed | Giovanni Campeggi † | Bishop of Poreč (Parenzo), Croatia | Bishop of Bologna, Italy | ||
| 38.4 | Appointed | Pietro Tagliavia d’Aragonia † | Bishop of Agrigento (Girgenti), Italy | Cardinal, Archbishop of Palermo, Italy | |
| 31 May | 64.8 | Appointed | Nikolaus von Schönberg, O.P. † | Cardinal-Priest of San Sisto | Cardinal, Archbishop Emeritus of Capua, Italy |
| 13 Jun | Appointed | Jean de Lettes † | Bishop of Béziers, France | Bishop Emeritus | |
| 17 Jun | 16.7 | Appointed | Alessandro Farnese (Jr.) † | Administrator of Bitonto, Italy | Cardinal, Cardinal-Bishop of Ostia (e Velletri) |
| Ordained Bishop | Jean Lunel, O. Cist. † | Titular Bishop of Sebaste in Cilicia | Auxiliary Bishop of Chartres, France | ||
| 19 Jun | Died | John Kite † | Bishop of Carlisle, England, Great Britain | ||
| 20 Jun | Appointed | Antonio Calcena, O.F.M. † | Bishop of Tortosa, Spain | ||
| 61.0 | Appointed | Gian Pietro Carafa † | Archbishop of Chieti, Italy | Pope (Roma {Rome}, Italy) | |
| 39.2 | Appointed | Jean de Lorraine † | Administrator of Lyon, France | Cardinal, Bishop of Metz, France | |
| Appointed | Giovanni Simonetta † | Bishop of Lodi, Italy | |||
| 62.5 | Resigned | Giacomo Simonetta † | Bishop of Lodi, Italy | Cardinal, Administrator of Nepi e Sutri, Italy | |
| 24 Jun | Died | Mario Maffei † | Bishop of Cavaillon, France | ||
| 26 Jun | 31.6 | Appointed | Ercole Gonzaga † | Administrator of Tarazona, Spain | Cardinal, Bishop of Mantova, Italy |
| 27 Jun | Appointed | Giacomo Antonio Ferduzi, O.F.M. Conv. † | Bishop of Martirano (Martoranum), Italy | ||
| Appointed | Jacques Leroy, O.S.B. † | Archbishop of Bourges, France | |||
| Appointed | Rafael Llinás, O. Carm. † | Auxiliary Bishop of Mallorca, Spain | |||
| 50.4 | Resigned | Johannes von Lupfen † | Bishop-Elect of Konstanz {Constance}, Germany | Former Bishop-Elect | |
| 48.5 | Resigned | François de Tournon, C.R.S.A. † | Archbishop of Bourges, France | Cardinal, Archbishop of Lyon, France | |
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