| Date | Age | Event | Bishop | Title | Current Title |
| unknown | | Born | Musa al-Akkari † | al-Baridah | Patriarch of Antiochia {Antioch} (Maronite), Lebanon |
| Died | Astorgius Almarici † | Archbishop of Vienne, France |
| Appointed | Domenico Antonio † | Bishop of Fano, Italy |
| Died | Giacomo Vittorio Appiani † | Bishop of Gravina (di Puglia), Italy |
| Born | Jean Bertrand † | Toulouse | Cardinal, Bishop Emeritus of (Saint-Bernard de) Comminges, France |
| Appointed | Alfonso de Burgos, O.P. † | Bishop of Cuenca, Spain | Bishop of Palencia, Spain |
| Died | Corrado Capece † | Archbishop of Benevento, Italy |
| Born | Marco Cornaro † | Venice | Cardinal, Cardinal-Bishop of Palestrina |
| Appointed | Johann von Dalberg † | Bishop of Worms, Germany |
| Appointed | Pietro Matteo d’Aquino † | Bishop of Gravina (di Puglia), Italy | Bishop of Lecce, Italy |
| Died | Tommaso della Testa Piccolomini † | Bishop of Pienza, Italy |
| Died | Giacomo di Santa Lucia, O.F.M. † | Bishop of Patti, Italy |
| Died | Vilem Kolina (Polonia), O.S.A. † | Auxiliary Bishop of Olomouc (Olmütz), Czech Republic |
| Born | Edward Lee † | | Archbishop of York, England, Great Britain |
| Died | Jean de Lévis † | Bishop of Lescar, France |
| Died | Antonius de Maffeis † | Bishop of Montepeloso, Italy |
| Born | Györgi Martinuzzi, O.S.P.P.E. † | Kamicac | Cardinal, Bishop of Oradea Mare {Gran Varadino, Nagyvárad}, Romania |
| Born | Agostino Spínola † | Savona | Cardinal, Administrator of Savona, Italy |
| Died | Giovanni di Renzo de Tonsis, O.F.M. † | Bishop of Fano, Italy |
| Jan | 59.0 | Died | Jacques d’Espinay-Durestal † | Bishop Emeritus of Rennes, France |
| 7 Jan | | Appointed | Lionel Wydeville (Woodville) † | Bishop of Salisbury, England, Great Britain |
| 13 Jan | | Ordained Bishop | Donato de Georgiis, O.P. † | Bishop of Trebinje e Mrkan, Bosnia and Herzegovina |
| 22 Jan | | Died | Heinrich Unkel, O.F.M. † | Auxiliary Bishop-Elect of Köln {Cologne}, Germany |
| 30 Jan | | Appointed | Hermann von Rethem, O.P. † | Auxiliary Bishop of Bremen (and Hamberg), Germany |
| Appointed | Hermann von Rethem, O.P. † | Titular Bishop of Sebaste in Cilicia | Auxiliary Bishop of Bremen (and Hamberg), Germany |
| 6 Mar | | Appointed | Francisco de Santillana † | Bishop of Córdoba, Spain |
| 7 Mar | | Born | Tomás de San Martín, O.P. † | Córdoba, Spain | Bishop of La Plata o Charcas, Bolivia |
| 20 Mar | 25.2 | Appointed | Julius Caesar Cantelmi † | Bishop of Montepeloso, Italy | Bishop Emeritus |
| 29 Mar | | Appointed | Michel Guibé † | Bishop of Rennes, France |
| Apr | 52.3 | Appointed | Ferry de Clugny † | Cardinal-Priest of Santa Maria in Domnica | Cardinal, Bishop of Tournai {Doornik}, Belgium |
| 14 Apr | 265.3 | Canonized | St. Bonaventura (Giovanni) , O.F.M. † | Cardinal, Cardinal-Bishop of Albano |
| 20 Apr | 42.3 | Appointed | Melchior von Meckau † | Coadjutor Bishop of Brixen {Bressanone}, Italy | Cardinal, Bishop |
| 21 Apr | | Ordained Bishop | Paulus † | Bishop of Ardjisch (Arges; Argesch), Romania |
| Ordained Bishop | Lionel Wydeville (Woodville) † | Bishop of Salisbury, England, Great Britain |
| 26 Apr | | Appointed | Sulpicio Acquaviva d’Aragona † | Bishop of Bitetto, France | Bishop of Conversano, Italy |
| Appointed | Jean Battista de Judicibus † | Archbishop of Amalfi, Italy | Archbishop Emeritus |
| Appointed | Richard Martin † | Bishop of Saint David’s, Wales, Great Britain |
| Appointed | Giovanni Nicolini † | Titular Archbishop of Athenae | Archbishop Emeritus of Amalfi, Italy |
| Resigned | Giovanni Nicolini † | Archbishop of Amalfi, Italy | Archbishop Emeritus |
| 29 Apr | | Appointed | Giovanni Nicolini † | Archbishop (Personal Title) of Verdun, France | Archbishop Emeritus of Amalfi, Italy |
| 30 Apr | | Born | Ludovico Chericato (Chierepati), O.F.M. † | | Archbishop Emeritus of Bar (Antivari), Montenegro |
| 6 May | 15.3 | Succeeded | Adalbert zu Sachsen † | Archbishop of Mainz, Germany | Archbishop-Elect |
| 7 May | 70.3 | Died | Diether von Isenburg-Büdingen † | Archbishop of Mainz, Germany |
| 21 May | 58.4 | Died | Konrad von Diepholz † | Bishop of Osnabrück, Germany |
| 27 May | | Appointed | Genesius † | Titular Archbishop of Mitylene |
| 10 Jun | | Died | Antoine Raguier † | Bishop of Lisieux, France |
| 13 Jun | | Appointed | Fabrizio Varano † | Bishop of Camerino, Italy |
| 17 Jun | | Appointed | Odon Ozic, O.S.A. † | Bishop of Vaison, France |
| 18 Jun | 22.5 | Selected | Georges d’Amboise (I) † | Archbishop of Narbonne, France | Cardinal, Archbishop of Rouen, France |
| 21 Jun | | Appointed | André Byssmann, O.S.A. † | Auxiliary Bishop of Olomouc (Olmütz), Czech Republic |
| Appointed | André Byssmann, O.S.A. † | Titular Bishop of Nicopolis ad Iaterum | Auxiliary Bishop of Olomouc (Olmütz), Czech Republic |
| Appointed | Pietro Palagario, O.F.M. † | Bishop of Lavello, Italy | Bishop of Telese o Cerreto Sannita, Italy |
| 25 Jun | | Died | Jean Coeur † | Archbishop of Bourges, France |
| 1 Jul | | Died | Alfonso Carrillo de Acuńa † | Archbishop of Toledo, Spain |
| 7 Jul | | Ordained Bishop | André Byssmann, O.S.A. † | Titular Bishop of Nicopolis ad Iaterum | Auxiliary Bishop of Olomouc (Olmütz), Czech Republic |
| 80.5 | Died | Walter Supersaxo † | Bishop of Sion {Sitten}, Switzerland |
| 8 Jul | 51.5 | Appointed | Rodrigo de Borja † | Administrator of Cartagena (en Espańa) | Pope (Roma {Rome}, Italy) |
| 21.2 | Appointed | Raffaele Sansone Riario † | Administrator of Salamanca, Spain | Cardinal, Bishop of Ostia (-Velletri), Italy |
| 12 Jul | | Appointed | Étienne Blosset de Carrouges † | Bishop of Lisieux, France |
| Appointed | Jacques de Caulers † | Bishop of Nîmes, France |
| 13 Jul | 26.5 | Selected | Konrad von Rietberg † | Bishop of Osnabrück, Germany |
| 19 Jul | 40.5 | Appointed | Domenico della Rovere † | Archbishop (Personal Title) of Genčve {Geneva}, Switzerland | Cardinal, Bishop of Corneto (Tarquinia) e Montefiascone, Italy |
| 24 Jul | | Appointed | Giovanni de Compesio (Compeys) † | Bishop of Genčve {Geneva}, Switzerland | Archbishop of Tarentaise (Moűtiers-en-Tarentaise), France |
| 40.6 | Appointed | Domenico della Rovere † | Archbishop (Personal Title) of Torino, Italy | Cardinal, Bishop of Corneto (Tarquinia) e Montefiascone, Italy |
| Appointed | Alessandro (Angelo) Geraldini † | Bishop of Kammin (Camin), Germany | Bishop of Sessa Aurunca, Italy |
| 28 Jul | | Ordained Bishop | Richard Martin † | Bishop of Saint David’s, Wales, Great Britain |
| Aug | | Died | Šimun Vosić (Vossich) † | Bishop of Capodistria (Capo d’Istria)(Koper), Slovenia |
| 7 Aug | | Appointed | Pierre Cadoet † | Archbishop of Bourges, France |
| 12 Aug | 65.6 | Died | Reinhard von Sickingen † | Bishop of Worms, Germany |
| 39.6 | Appointed | Andrew Stewart † | Bishop of Moray, Scotland, Great Britain |
| 25 Aug | | Died | Protasius von Czernahora † | Bishop of Olomouc (Olmütz), Czech Republic |
| Died | Sagramoro Sagramori † | Bishop of Parma, Italy |
| 30 Aug | | Died | Louis de Bourbon † | Bishop of Ličge, Belgium |
| Appointed | Jacques Valaresso † | Bishop of Capodistria (Capo d’Istria)(Koper), Slovenia |
| 15 Sep | | Died | Giovanni de Mondani † | Bishop of Bobbio, Italy |
| 21 Sep | 55.7 | Died | Georg Heßler (Hessler) † | Cardinal, Bishop of Passau, Germany |
| 23 Sep | 48.7 | Appointed | Girolamo Basso Della Rovere † | Administrator of Gubbio, Italy | Cardinal, Bishop of Macerata, Italy |
| Appointed | Leonardo Grifo † | Archbishop of Benevento, Italy |
| 2 Oct | | Appointed | Gabriel de Franchis, O.P. † | Bishop of Ajaccio, France |
| 7 Oct | | Appointed | Lucchino Trotti † | Bishop of Bobbio, Italy |
| 13 Oct | | Ordained Bishop | Gabriel de Franchis, O.P. † | Bishop of Ajaccio, France |
| 18 Oct | | Died | Pietro Guglielmo de Rocha † | Archbishop of Salerno, Italy |
| 20 Oct | | Ordained Bishop | Odon Ozic, O.S.A. † | Bishop of Vaison, France |
| 27 Oct | | Ordained Bishop | Pierre Cadoet † | Archbishop of Bourges, France |
| 30 Oct | | Appointed | Troilo Agnesi † | Bishop of Penne e Atri, Italy | Bishop of Lavello, Italy |
| Appointed | Friedrich Mauerkircher † | Bishop of Passau, Germany |
| 4 Nov | | Appointed | Johann Spenner (Spender), O.F.M. † | Auxiliary Bishop of Köln {Cologne}, Germany |
| Appointed | Johann Spenner (Spender), O.F.M. † | Titular Bishop of Cyrene | Auxiliary Bishop of Köln {Cologne}, Germany |
| 6 Nov | | Appointed | Erasmus Perchinger, O.F.M. † | Auxiliary Bishop of Freising, Germany |
| Appointed | Erasmus Perchinger, O.F.M. † | Titular Bishop of Saldae | Auxiliary Bishop of Freising, Germany |
| 11 Nov | 26.9 | Confirmed | Konrad von Rietberg † | Bishop of Osnabrück, Germany |
| 13 Nov | 54.5 | Appointed | Pedro González de Mendoza † | Cardinal, Archbishop of Toledo, Spain |
| 54.5 | Appointed | Pedro González de Mendoza † | Titular Patriarch of Alexandria {Alessandria} | Cardinal, Archbishop of Toledo, Spain |
| 18 Nov | | Ordained Bishop | Erasmus Perchinger, O.F.M. † | Titular Bishop of Saldae | Auxiliary Bishop of Freising, Germany |
| Ordained Bishop | Johann Spenner (Spender), O.F.M. † | Titular Bishop of Cyrene | Auxiliary Bishop of Köln {Cologne}, Germany |
| 30 Dec | 31.3 | Appointed | Gian Giacomo Schiaffinato † | Cardinal, Bishop of Parma, Italy |