| Date | Age | Bishop | Title |
| unknown | | David ap Yeworth † | Bishop of Saint Asaph, Wales, Great Britain |
| unknown | | Antonio de Miraballis † | Bishop of Lettere (-Gragnano), Italy |
| unknown | | Gaspare Golfi, O.F.M. † | Bishop of Cagli, Italy |
| unknown | | Lodovico † | Bishop of Civita Castellana e Orte, Italy |
| unknown | | Francesco Oricellai † | Bishop of Pesaro, Italy |
| unknown | | Jean Orient, O.F.M. † | Bishop of Terralba, Italy |
| unknown | | Orlando Orsini † | Bishop of Nola, Italy |
| unknown | | Juan Ortega † | Bishop-Elect of Potenza, Italy |
| unknown | | Juan Pérez † | Bishop of Ottana, Italy |
| unknown | | Geronimo Porcari † | Bishop of Andria, Italy |
| unknown | | Giovanni Robobello † | Archbishop of Zadar (Zara), Croatia |
| unknown | | Pietro Strambone, O.P. † | Bishop of Nocera de’ Pagani, Italy |
| unknown | | Heinrich von Höwen † | Bishop of Chur, Switzerland |
| 29 Jan | | Edward Story † | Bishop of Chichester, England, Great Britain |
| 15 Feb | 63.1 | Henry Deane † | Archbishop of Canterbury, England, Great Britain |
| 22 Feb | 53.1 | Giovanni Battista Orsini † | Cardinal, Cardinal-Priest of Santi Giovanni e Paolo |
| 9 Mar | | Jacques Valaresso † | Bishop of Capodistria (Capo d'Istria)(Koper), Slovenia |
| 14 Mar | 35.0 | Fryderyk Jagiellończyk † | Cardinal, Archbishop of Gniezno, Poland |
| 1 Apr | | Jean Milet † | Bishop of Soissons, France |
| 10 Apr | 57.3 | Giovanni Michiel † | Cardinal, Bishop of Verona, Italy |
| 2 Jul | | Nikolaus Kreuder, O.T. † | Bishop of Samland, Poland |
| 3 Jul | 80.5 | Pierre d’Aubusson, O.S.Io.Hieros. † | Cardinal, Grand Master of Sovereign Military Hospitaller Order of St John of Jerusalem |
| 16 Jul | | Jérôme von Reitzenstein, O. Cist. † | Auxiliary Bishop of Bamberg, Germany |
| 28 Jul | | Johann von Dalberg † | Bishop of Worms, Germany |
| 31 Jul | | Alessandro Carafa † | Archbishop of Napoli {Naples}, Italy |
| 1 Aug | 57.6 | Juan de Borja Lanzol de Romaní † | Cardinal, Archbishop of Monreale, Italy |
| 18 Aug | 72.6 | Rodrigo de Borja † | Pope (Roma {Rome}, Italy) |
| 18 Aug | | Gerolamo Pallavicini † | Bishop of Novara, Italy |
| 29 Aug | 71.7 | Oliver King † | Bishop of Bath and Wells, England, Great Britain |
| Sep | | Antonio Corseto † | Bishop of Malta |
| 7 Sep | | Veit Truchseß von Pommersfelden † | Bishop-Elect of Bamberg, Germany |
| 18 Oct | 64.4 | Francesco Todeschini-Piccolomini † | Pope (Roma {Rome}, Italy) |
| 1 Dec | 22.5 | Ruprecht von Rhein † | Former Bishop-Elect of Freising, Germany |
| 5 Dec | | Johann Spenner (Spender), O.F.M. † | Auxiliary Bishop of Köln {Cologne}, Germany |
| 21 Dec | 54.0 | Lorenzo Cibo de’ Mari † | Cardinal, Archbishop Emeritus of Benevento, Italy |
| 27 Dec | | Andrea de Conto (Cuncto) † | Archbishop of Amalfi, Italy |